VTD

Vichag Trials Digest

Vichag Trials Digest is a monthly snapshot of recently-published innovatively designed clinical trials led through independent community clinics. The digest highlights pragmatic study designs, operational insights, and trial models that can inspire sponsors, sites, and trialists alike.

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July 2026

Obërtinca et al., British Journal of Sports Medicine, 2024

A cluster-randomized controlled trial across 55 youth football teams evaluating whether a structured, exercise-based injury prevention programme (“FUNBALL”) could reduce injury incidence over a full season. The study highlights the effectiveness of simple, team-integrated training interventions delivered within real-world club settings to meaningfully reduce overall and severe lower-limb injuries in adolescent athletes.

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June 2026

IMPACTS-BP Consortium, NEJM 2026

A pragmatic cluster-randomized trial across 36 US independant health center clinics evaluating whether team-based, protocol-driven hypertension management could improve blood pressure control in low-income populations. The study highlights community-based research networks, task-sharing models, and home monitoring in delivering high-impact clinical care and research.

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May 2026

HEALing Consortium, NEJM 2024

A landmark community-based cluster-randomized trial across 67 U.S. communities evaluating whether locally-driven opioid interventions could reduce overdose deaths. The study offers valuable lessons in pragmatic trial design, implementation frameworks, and the power of independent community clinic research networks.

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